Canadian October home sales dip, latest sign of cooling

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TORONTO (Reuters) – Sales of existing homes in Canada fell in October from September and year-over-year sales were down as well, the Canadian Real Estate Association said on Thursday in the latest signal that the housing market is slowing.


The industry group for Canadian real estate agents said sales were down 0.1 percent in October from September. Actual sales for October, not seasonally adjusted, were down 0.8 percent from a year earlier.













The housing market, which roared higher in 2011 and the first half of 2012, started to slow after the government tightened rules on mortgage lending in July in a bid to cool the market and prevent home buyers from taking on too much debt.


Housing market trends in Canada for 2012 can be characterized as before and after regulatory changes,” TD Economics senior economist Sonya Gulati said in a research note.


“In the first half of the year, sales and price gains were modest, but positive. More stringent mortgage rules and tighter mortgage underwriting rules have ‘purposely’ knocked the wind out of the housing market sails,” she said.


The home sales data showed diverging paths in Canadian housing depending on location. In Toronto and Vancouver, where sales and price gains were red hot in 2011 and early in 2012, the market has been cooling. But markets in the resource-rich western provinces of Saskatchewan and Alberta have been gaining strength.


“Opinions differ about how sharply sales have slowed depending on the local housing market,” Gregory Klump, CREA’s chief economist, said in a statement.


Led by Calgary, sales in October were up from a year earlier in almost two-thirds of local markets. Sales remained blow year-earlier levels in Toronto, Vancouver and Montreal, CREA said.


“These results suggest that the Canadian housing market overall has returned to a more sustainable pace,” Klump said.


CREA’s Home Price Index rose 3.6 percent in October from a year earlier, the sixth consecutive month in which gains in prices slowed, and the slowest rate of increase since May 2011.


While tighter mortgage rules have worked to slow the market, TD’s Gulati said the big question is what will happen when that temporary cooling effect wears off in early 2013.


“What happens thereafter is less certain. The low interest rate environment could pull homeowners back onto the market, causing home prices to once again trek upwards. Alternatively, an absence of pent-up demand may leave the market in a bit of a lull until interest rate hikes resume in late 2013,” she wrote.


“Under either scenario, it is safe to say that there is a low probability of out-sized home price gains over the near-term.”


A total of 402,322 homes traded hands via Canadian MLS systems over the first 10 months of 2012, up 0.8 percent from the same period last year and 0.4 percent below the 10-year average for the period, the data showed.


The number of newly listed homes fell 3.8 percent in October following a jump in September. Monthly declines were reported in almost two-thirds of local markets, with Toronto and Vancouver exerting a large influence on the national trend.


Nationally, there were 6.5 months of inventory at the end of October, little changed from the reading of 6.4 months at the end of September.


(Editing by Peter Galloway)


Canada News Headlines – Yahoo! News



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How new Kindle Fire compares with rivals

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Amazon.com Inc. started shipping a larger version of its Kindle Fire HD tablet computer on Thursday. Here’s a look at how it compares with the iPad and other tablets with similar screens.


Amazon.com Inc.‘s Kindle Fire HD 8.9″:













— Price: $ 299 for 16 gigabytes of storage, $ 369 for 32 GB.


Screen size: 8.9 inches diagonally


— Screen resolution: 1920 by 1200 pixels, at 254 pixels per inch.


— Weight: 1.25 pounds.


— Cameras: Front-facing camera.


— Battery life: 10 hours.


— Operating system: Modified version of Google‘s Android


Pros: Cheap and portable. Convenient access to Amazon store. Dolby audio. Available with access to fast 4G wireless broadband networks, for $ 499 (starts shipping next Tuesday).


Cons: Small selection of third-party applications available from Amazon. No rear camera for taking video and photos.


Apple Inc.‘s iPad:


— Price: Starts at $ 499 for 16 gigabytes of storage, goes up to $ 699 for 64 gigabytes, more for versions with cellular data access. (Apple still sells the older, iPad 2 for $ 399.)


Screen size: 9.7 inches diagonally


— Screen resolution: 2048 by 1536 pixels, at 264 pixels per inch.


— Weight: 1.44 pounds


— Cameras: 5-megapixel camera on back and a low-resolution camera on front, for videoconferencing


— Battery life: 10 hours.


— Operating system: Apple’s iOS


Pros: Unmatched access to third-party applications, high-quality Apple software and the iTunes store. Widest range of cases and accessories available. Available with access to fast 4G wireless broadband networks, starting at $ 629.


Cons: Data storage cannot be expanded with memory cards.


Google Inc.’s Nexus 10


— Price: $ 399 for 16 gigabytes of storage, $ 499 for 32 GB


Screen size: 10.1 inches diagonally


— Screen resolution: 2560 by 1600 pixels, at 300 pixels per inch.


— Weight: 1.33 pounds.


— Cameras: 5-megapixel camera on back and a low-resolution camera on front, for videoconferencing


— Battery life: 9 hours for video playback, 7 hours for Web browsing.


— Operating system: Google‘s Android


Pros: Access to a variety of games, utilities and other software for Android devices, though not as extensive as apps available for iPad. Longer, narrower screen better suited to movies. Cheaper than newest full-size iPad.


Cons: Integrates with Google Play store, which is still new and isn’t as robust as Apple or Amazon’s stores. Data storage cannot be expanded with memory cards. No option for cellular wireless broadband.


Samsung Electronic Co.’s Galaxy Tab 2 10.1:


— Price: $ 399 for 16 gigabytes of storage


Screen size: 10.1 inches diagonally


— Screen resolution: 1280 by 800 pixels, 149 pixels per inch


— Weight: 1.24 pounds


— Cameras: low-resolution front camera, 3-megapixel back.


— Battery life: 11 hours.


— Operating system: Google‘s Android


Pros: Storage is expandable with microSD memory cards. Can act as a universal remote control for an entertainment center. Option for wireless broadband starting in November.


Cons: Selection of third-party applications not as good as iPad’s, but wider than Kindle. Screen resolution lower than iPad’s.


Samsung Electronic Co.’s Galaxy Note 10.1:


— Price: $ 499 for 16 gigabytes of storage, $ 549 for 32 GB


Screen size: 10.1 inches diagonally


— Screen resolution: 1280 by 800 pixels, 149 pixels per inch


— Weight: 1.3 pounds


— Cameras: low-resolution front camera, 5-megapixel back.


— Battery life: 9 hours.


— Operating system: Google‘s Android


Pros: Comes with a pen, for jotting notes and drawing on the screen. Slightly thinner and lighter than an iPad. Longer, narrower screen better suited to movies. Storage is expandable with microSD memory cards. Can act as a universal remote control for an entertainment center.


Cons: Selection of third-party applications not as good as iPad’s, but wider than Kindle. Screen resolution lower than iPad’s. No option for wireless broadband. Pen sensor slightly shortens battery life.


Barnes & Noble Inc.’s Nook HD+


— Price: $ 269 for 16 gigabytes of storage; $ 299 for 32 GB


Screen size: 9 inches diagonally


— Screen resolution: 1920 x 1280 pixels, 256 pixels per inch


— Weight: 1.14 pounds


— Cameras: None.


— Battery life: 10 hours of reading, 9 hours of video


— Operating system: Modified version of Google‘s Android


Pros: Cheap and portable. Storage is expandable with microSD memory cards. Easy access to Barnes & Noble book store.


Cons: Selection of third-party applications is small. Barnes & Noble lacks wide range of content. Lacks cameras and option for wireless broadband.


Microsoft Corp.’s Surface:


— Price: $ 499 for 32 gigabytes of storage, $ 100 extra for keyboard cover. $ 699 for 64 GB version, includes keyboard cover.


Screen size: 10.6 inches diagonally


— Screen resolution: 1366 by 768 pixels, 148 pixels per inch


— Weight: 1.5 pounds.


— Cameras: Front and back cameras


— Battery life: 8 hours.


— Operating system: Microsoft’s Windows RT.


Pros: Storage can be expanded with microSD memory cards. Comes with free Microsoft Office software. Models running full version of Windows 8 coming soon, offering compatibility with programs available for traditional Windows computers.


Cons: Operating system lacks good track record on tablets. Selection of tablet-adapted third-party applications small. No option for wireless broadband.


Gadgets News Headlines – Yahoo! News



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“Sister” Director Tackles Taboo of Switzerland’s Class Divide With Her Oscar Contender

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LOS ANGELES (TheWrap.com) – Director Ursula Meier can hardly believe that her film “Sister” – which depicts tenements, poverty and a seemingly rigid class system in lovely Switzerland – has made it over the Alps to Hollywood for Academy consideration.


“It shows a not-very-usual aspect of Switzerland,” Meier told the audience at a showing of “Sister” Thursday night at the Landmark, part of TheWrap’s Academy Screening Series. “We don’t show the beautiful mountains and the green and the lush life … For me it was important to show another point of view on this country to the world. Because usually it’s Montblanc, chocolate, and Swatch.”













Indeed, with her second film, Meier has given international audiences something else to associate with Switzerland: larcenous snow urchins.


“Sister” centers mostly around 12-year-old Simon (Kacey Mottet Klein), who lives in a high-rise tenement in a not-so-snowy valley far below a ski resort and takes gondolas to the top to steal wealthy tourists’ skis right out from under their goggles.


Wily Simon is financing not just his own existence but that of Louise (Lea Seydoux), the title character, who just might be the worst parental figure or caretaker in a cinematic year that did, after all, include “Beasts of the Southern Wild.”


It would involve spoilers to explain why Simon’s older sis is not everything she’s cracked up to be. But there’s nothing misleading about this boy-crazy, substance-abusing twentysomething gal’s unfitness to watch over Simon, the breadwinner of their sad two-person family.


He has to empty out his cash drawer to bribe Louise into snuggling with him, and when he entrusts her with the mere task of waxing skis, she can’t even do that without spilling cigarette ashes on the stolen merchandise.


“It was important for me, when we were at the ski resort, to showing the back door of the restaurant, and the workers inside … And it’s just at the end, when it’s finished, when there is no more snow and the ski resort is closed, for the first time Simon looks at the landscape. And we can see how beautiful this place is, but it’s too late now.”


Meier worked with her young leading man on her first theatrical feature, 2009′s “Home,” where he played Isabella Huppert’s son when he was just 7. She’s emphatic that Klein is not the kind of child actor who has to be tricked into giving a performance.


“During the first casting, I ask him, ‘What do you like to do in your life, Kasey?’ And he told me, ‘Thinking.’ So I said ‘OK, think,’ and I turned on the camera, and he was amazing … He understands that acting is to be, not to look like. So I really wanted to write for him with this film, because it was such an amazing experience on my first film.”


The role of the severely neglectful “sister” was tougher to nail down, both for the director and her leading actress.


“This character was the challenge of the film,” Meier said. “Because Kacey’s character is a child, so for the spectator, of course he’s a victim. But with the character of Louise, for Lea as an actress, at the beginning for her it was very hard to find the fragility of the character. I showed her a lot of films like ‘Vagabond’ … I explained to her, you were 14 when you were pregnant; it was too young for a girl, and you stopped your studies and got bad jobs you cut with your family.”


Sometimes, she said, they’d fight because “she couldn’t find the fragility of the character, and suddenly, months later, wow – it was like we cut something open and all the emotion that came out from her was very deep. I was afraid of the spectators judging the character. It was not easy, in the writing, or in the directing with the actors, because I wanted that they would love these characters, even if they’re sometimes terrible. But I like terrible characters.”


Pond told Meier that when it came to supporting actress Gillian Anderson, of “X-Files” fame, “the first time I watched, I didn’t realize it was her till the end credits” – an experience probably shared by most of those in attendance at the screening.


“I’m very happy that you say that,” said Meier, “because if you recognize the actress, you think about the actress.” But the director did want Armstrong to provoke a where-have-I-seen-you-before vibe.


“I really wanted to be played by a star – not to have a star in my film, but because it was important for Simon to have a kind of phantasma this lady, of what he wants as a mother.


And as a spectator, you can have a phantasma on the star. So I like that she came from another country, and not speak French, because she’s almost an apparition.”


Meier admitted she was frightened before the Swiss premiere – before “Sister” went on to play various fests and win the special Golden Bear award at the Berlin Film Festival.


“When I had the first screening in Switzerland, a lady came back to me and was very moved by the film, because it’s usually a taboo to show poverty in Switzerland. She cried and told me, ‘I grew up in exactly the same place. My father was a worker in the factory we saw in the film, and as a child we never had the money to go up.’ I liked that she just said up.”


Movies News Headlines – Yahoo! News



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Tulsa Town Hall: Nutrition a valuable tool in health care

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Weil spoke as part of the Tulsa Town Hall series of speakers.













The United States has an expensive health-care system that doesn’t produce good results, he said.


“Something is very wrong with this picture,” he said. “We’re spending more and more and we have less and less to show for it.”


Changes in diet can be an effective treatment for many conditions, but American physicians are functionally illiterate in nutrition, he said.


“The whole subject of nutrition is omitted in medical education,” he said.


There are many ways of managing diseases other than drugs, he said. Integrative medicine, which can include dietary supplements and practices like meditation, is the future of health care, he said.


The health system is resistant to change because of entrenched vested interests. That includes pharmaceutical companies that do direct-to-consumer advertising, which should be stopped, he said.


“As dysfunctional as our health-care system is at the moment – and it is very dysfunctional – it is generating rivers of money,” he said. “That money is going into very few pockets.”


Weil has developed an anti-inflammatory diet based on the Mediterranean diet but with Asian influences.


Inflammation is associated with some heart disease, Alzheimer’s disease and some cancers, he said. And as a result, people should be eating real, unprocessed foods and whole grains. They should stay away from sugar-sweetened beverages, including fruit juice, he said.


“The new research that’s being done on sugar is not very comforting,” he said.


The aging process can’t be avoided, but age-related diseases can be avoided by proper care, he said.


“The goal should be to live long and well with a big drop off at the end,” he said.


Weil is the director of the University of Arizona’s Center for Integrative Medicine.


Tickets to the Tulsa Town Hall series are sold as a $ 75 subscription and cover five lectures. Tickets for individual lectures are not available.


To subscribe, visit tulsaworld.com/tulsatownhall, call 918-749-5965 or write to: Tulsa Town Hall, Box 52266, Tulsa, OK 74152.


Future speakers include journalist Ann Compton on Feb. 8; author James B. Stewart on April 5; historian and cinematographer Rex Ziak on May 10.


Original Print Headline: Speaker highlights nutrition



Shannon Muchmore 918-581-8378
shannon.muchmore@tulsaworld.com3ed48  basic Tulsa Town Hall: Nutrition a valuable tool in health care
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Israel bombards Gaza Strip, shoots down rocket

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GAZA CITY, Gaza Strip (AP) — Israel bombarded the Hamas-ruled Gaza Strip with about 300 airstrikes Saturday and shot down a Palestinian rocket fired at Tel Aviv, the military said, widening a blistering assault to include the Hamas prime minister's headquarters, a police compound and a vast network of smuggling tunnels.

The intensified airstrikes came as Egyptian-led attempts to broker a cease-fire and end Israel's four-day-old Gaza offensive gained momentum. The leaders of Hamas and two key allies, Qatar and Turkey, were in Cairo for talks with Egyptian officials, and the Arab League was holding an emergency meeting.

The White House said President Barack Obama was also in touch with the Egyptian and Turkish leaders. The U.S. has solidly backed Israel so far.

Speaking on Air Force One, deputy national security adviser Ben Rhodes said that the White House believes Israel "has the right to defend itself" against attack and that the Israelis will make their own decisions about their "military tactics and operations."

The Israeli attacks, which Gaza officials say left 12 dead, came as Palestinian militants fired more than 100 rockets toward Israel, including two aimed at the commercial and cultural center of Tel Aviv. Rocket attacks on Tel Aviv and Jerusalem this week mark the first time Gaza militants have managed to fire rockets toward the cities, raising the stakes in the confrontation.

The widened scope of targets brings the scale of fighting closer to that of the war the two groups waged four years ago. Hamas was badly bruised during that conflict, but has since restocked its arsenal with more and better weapons, and has been under pressure from smaller, more militant groups to prove its commitment to fighting Israel.

In a psychological boost for the Israelis, a sophisticated Israeli rocket-defense system known as "Iron Dome" knocked down one of the rockets headed toward Tel Aviv, eliciting cheers from relieved residents huddled in fear after air raid sirens sounded in the city.

Associated Press video showed a plume of smoke rising from a rocket-defense battery deployed near the city, followed by a burst of light overhead. The smoke trailed the intercepting missile.

Police said a second rocket also targeted Tel Aviv. It was not clear where it landed or whether it was shot down. No injuries were reported. It was the third straight day the city was targeted.

Israel says the Iron Dome system has shot down some 250 incoming rockets, most of them in southern Israel near Gaza.

Saturday's interception was the first time Iron Dome has been deployed in Tel Aviv. The battery was a new upgraded version that was only activated on Saturday, two months ahead of schedule, officials said.

Israel opened the offensive on Wednesday with a surprising airstrike that killed Hamas' military chief, then attacked dozens of rocket launchers and storage sites. It says the offensive is meant to halt months of rocket fire on southern Israel.

While Israel claims to be inflicting heavy damage on Gaza's Hamas rulers, it has failed to slow the rocket fire. In all, 42 Palestinians, including 13 civilians, have been killed, while three Israeli civilians have died.

Maj. Gen. Tal Russo, Israel's southern commander, said Saturday that Hamas had suffered a tough blow.

"Most of their capabilities have been destroyed," he told reporters. Asked whether Israel is ready to send ground troops into Gaza, he said: "Absolutely."

Israel has authorized the call-up of as many as 75,000 reservists ahead of a possible ground operation. Dozens of armored vehicles have massed along the border with Gaza in recent days.

Israeli officials say they have not yet decided whether to send in ground troops, a decision that would almost certainly lead to heavy casualties on both sides.

In Saturday's fighting, Israeli aircraft pounded militants' weapons storage facilities and underground rocket launching sites, and went after rocket squads more aggressively.

Militants, undaunted, have unleashed some 500 rockets against the Jewish state.

Hamas claims that Israeli intelligence is based on a network of collaborators in Gaza. Officials said two Palestinians have been executed by Hamas' military wing for allegedly providing Israel with sensitive information. One man was shot twice in the head. Another body was tossed into a garbage bin with a gunshot wound to the head.

The violence has threatened the Mideast with a new war. At the same time, revolts against entrenched regional regimes have opened up new possibilities for Hamas. Islamists across the Mideast have been strengthened, bringing newfound recognition to Hamas, which had previously been shunned by the international community because of its refusal to recognize Israel and renounce violence.

A high-level Tunisian delegation, led by Foreign Minister Rafik Abdessalem, drove that point home with a visit to Gaza on Saturday. The foreign minister's first stop was the still-smoldering ruins of the three-story office building of Gaza's prime minister, Ismail Haniyeh of Hamas.

"Israel has to understand that there is an international law and it has to respect the international law to stop the aggression against the Palestinian people," Abdessalem told the AP during a tour of Gaza's main hospital. He said his country was doing whatever it can to promote a cease-fire, but did not elaborate.

It was the first official Tunisian visit since Hamas's violent 2007 takeover of the territory. The West Bank is governed by Palestinian President Mahmoud Abbas. Egypt's prime minister visited Gaza on Friday and a Moroccan delegation was due on Sunday, following a landmark visit by Qatar's leader last month.

Israel had been incrementally expanding its operation beyond military targets but before dawn on Saturday it ramped that up dramatically, hitting Hamas symbols of power.

Israeli defense officials, speaking on condition of anonymity to discuss confidential decisions, said military chief Lt. Gen. Benny Gantz personally ordered the scope of the airstrikes to be increased.

Haniyeh's three-story office building was flattened by an airstrike that blew out windows in neighboring homes. He was not inside the building at the time.

Another airstrike brought down the three-story home of a Hamas commander in the Jebaliya refugee camp near Gaza City, critically wounding him and injuring other residents of the building, medics said.

Missiles smashed into two small security facilities and the massive Hamas police headquarters in Gaza City, setting off a huge blaze that engulfed nearby houses and civilian cars parked outside, the Interior Ministry reported. No one was inside the buildings.

The Interior Ministry said a government compound was also hit while devout Muslims streamed to the area for early morning prayers, although no casualties were reported.

Air attacks knocked out five electricity transformers, cutting off power to more than 400,000 people in southern Gaza, according to the Gaza electricity distribution company. People switched on backup generators for limited electrical supplies.

In southern Gaza, aircraft went after underground tunnels militants use to smuggle in weapons and other contraband from Egypt, residents reported. A huge explosion in the area sent buildings shuddering in the Egyptian city of El-Arish, 45 kilometers (30 miles) away, an Associated Press correspondent there reported.

The Israeli military said more than 950 targets have been struck since the operation began.

On Saturday, more than 120 rockets slammed into Israel, causing damage to houses. About 10 Israelis were injured lightly, among dozens of others wounded since the start of the operation.

Despite the violence, Egyptian-led diplomacy was underway to bring an end to the fighting.

Egyptian President Mohammed Morsi was meeting the leaders of Turkey and Qatar Saturday as well as Hamas leader Khaled Meshal to discuss details of a proposed cease-fire.

The Arab League also met Saturday to consider sending its chief Nabil Elaraby and a team of foreign ministers to Gaza in the coming two days to assess the situation and respond to humanitarian needs there, according to a draft memorandum obtained by the AP.

Turkish Prime Minister Recep Tayyip Erdogan told reporters Saturday that during discussions with Obama and Russian President Vladimir Putin late Friday, he suggested that Turkey, Egypt, the United States and Russia help broker a simultaneous cease-fire between Israel and Hamas.

"It would be good if we could work on it rapidly to solve the matter within 24 hours, because the death toll is mounting," he said.

___

Goldenberg reported from Jerusalem. Associated Press writers Karin Laub in Gaza City, Matthew Daly in Washington and Aya Batrawy in Cairo contributed reporting.

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Israel moves on reservists after rockets target cities

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GAZA/JERUSALEM (Reuters) – Israeli ministers were on Friday asked to endorse the call-up of up to 75,000 reservists after Palestinian militants nearly hit Jerusalem with a rocket for the first time in decades and fired at Tel Aviv for a second day.


The rocket attacks were a challenge to Israel‘s Gaza offensive and came just hours after Egypt‘s prime minister, denouncing what he described as Israeli aggression, visited the enclave and said Cairo was prepared to mediate.













Israel’s armed forces announced that a highway leading to the Gaza Strip and two roads bordering the enclave would be off-limits to civilian traffic until further notice.


Tanks and self-propelled guns were seen near the border area on Friday, and the military said it had already called 16,000 reservists to active duty.


Prime Minister Benjamin Netanyahu convened senior cabinet ministers in Tel Aviv after the rockets struck to decide on widening the Gaza campaign.


Political sources said ministers were asked to approve the mobilization of up to 75,000 reservists, in what could be preparation for a possible ground operation.


No decision was immediately announced and some commentators speculated in the Israeli media the move could be psychological warfare against Gaza’s Hamas rulers. A quota of 30,000 reservists had been set earlier.


Israel began bombing Gaza on Wednesday with an attack that killed the Hamas military chief. It says its campaign is in response to Hamas missiles fired on its territory. Hamas stepped up rocket attacks in response.


Israeli police said a rocket fired from Gaza landed in the Jerusalem area, outside the city, on Friday.


It was the first Palestinian rocket since 1970 to reach the vicinity of the holy city, which Israel claims as its capital, and was likely to spur an escalation in its three-day old air war against militants in Gaza.


Rockets nearly hit Tel Aviv on Thursday for the first time since Saddam Hussein’s Iraq fired them during the 1991 Gulf War. An air raid siren rang out on Friday when the commercial centre was targeted again. Motorists crouched next to cars, many with their hands protecting their heads, while pedestrians scurried for cover in building stairwells.


The Jerusalem and Tel Aviv strikes have so far caused no casualties or damage, but could be political poison for Netanyahu, a conservative favored to win re-election in January on the strength of his ability to guarantee security.


“The Israel Defence Forces will continue to hit Hamas hard and are prepared to broaden the action inside Gaza,” Netanyahu said before the rocket attacks on the two cities.


Asked about Israel massing forces for a possible Gaza invasion, Hamas spokesman Sami Abu Zuhri said: “The Israelis should be aware of the grave results of such a raid and they should bring their body bags.”


Officials in Gaza said 28 Palestinians had been killed in the enclave since Israel began the air offensive with the declared aim of stemming surges of rocket strikes that have disrupted life in southern Israeli towns.


The Palestinian dead include 12 militants and 16 civilians, among them eight children and a pregnant woman. Three Israelis were killed by a rocket on Thursday. A Hamas source said the Israeli air force launched an attack on the house of Hamas’s commander for southern Gaza which resulted in the death of two civilians, one a child.


SOLIDARITY VISIT


A solidarity visit to Gaza by Egyptian Prime Minister Hisham Kandil, whose Islamist government is allied with Hamas but also party to a 1979 peace treaty with Israel, had appeared to open a tiny window to emergency peace diplomacy.


Kandil said: “Egypt will spare no effort … to stop the aggression and to achieve a truce.”


But a three-hour truce that Israel declared for the duration of Kandil’s visit never took hold. Israel said 66 rockets launched from the Gaza Strip hit its territory on Friday and a further 99 were intercepted by the Iron Dome anti-missile system.


Israel denied Palestinian assertions that its aircraft struck while Kandil was in the enclave.


Israel Radio’s military affairs correspondent said the army’s Homefront Command had told municipal officials to make civil defence preparations for the possibility that fighting could drag on for seven weeks. An Israeli military spokeswoman declined to comment on the report.


The Gaza conflagration has stoked the flames of a Middle East already ablaze with two years of Arab revolution and a civil war in Syria that threatens to leap across borders.


It is the biggest test yet for Egypt’s new President Mohamed Mursi, a veteran Islamist politician from the Muslim Brotherhood who was elected this year after last year’s protests ousted military autocrat Hosni Mubarak.


Egypt’s Muslim Brotherhood are spiritual mentors of Hamas, yet Mursi has also pledged to respect Cairo’s 1979 peace treaty with Israel, seen in the West as the cornerstone of regional security. Egypt and Israel both receive billions of dollars in U.S. military aid to underwrite their treaty.


Mursi has vocally denounced the Israeli military action while promoting Egypt as a mediator, a mission that his prime minister’s visit was intended to further.


A Palestinian official close to Egypt’s mediators told Reuters Kandil’s visit “was the beginning of a process to explore the possibility of reaching a truce. It is early to speak of any details or of how things will evolve”.


Hamas fighters are no match for the Israeli military. The last Gaza war, involving a three-week long Israeli air blitz and ground invasion over the New Year period of 2008-2009, killed more than 1,400 Palestinians, mostly civilians. Thirteen Israelis died.


Tunisia’s foreign minister was due to visit Gaza on Saturday “to provide all political support for Gaza” the spokesman for the Tunisian president, Moncef Marzouki, said in a statement.


The United States asked countries that have contact with Hamas to urge the Islamist movement to stop its rocket attacks.


Hamas refuses to recognize Israel’s right to exist. By contrast, Palestinian President Mahmoud Abbas, who rules in the nearby West Bank, does recognize Israel, but peace talks between the two sides have been frozen since 2010.


Abbas’s supporters say they will push ahead with a plan to have Palestine declared an “observer state” rather than a mere “entity” at the United Nations later this month.


(Additional reporting by Maayan Lubell, Jeffrey Heller and Crispian Balmer in Jerusalem; Writing by Jeffrey Heller; Editing by Giles Elgood)


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“30 Rock” character Liz Lemon to get her happy ending

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LOS ANGELES (Reuters) – “30 Rock” perpetual unlucky-in-love heroine Liz Lemon is finally getting her happy ending, as NBC invited fans on Thursday to watch her get married this month.


After a string of bad boyfriends and unsuccessful romances, Lemon, played by comedienne Tina Fey, finds her soul mate in budding entrepreneur Criss Chross, who owns an organic gourmet hotdog food truck, played by actor James Marsden on the show.













“Ms. Elizabeth Miervaldis Lemon presents herself to be married to Mr. Crisstopher Rick Chross…But not in a creepy way that perpetuates the idea that brides are virgins and women are property,” NBC said in a mock wedding announcement, true to Lemon‘s feminist principles.


The wedding episode will be aired on November 29, during the Emmy-winning show’s seventh and final season.


While Lemon, 42, has never made it down the aisle before, she has had a couple of doomed engagements in past seasons, including her British boyfriend Wesley Snipes (Michael Sheen), whom she almost settled for before finding love with pilot Carol Burnett (Matt Damon).


The hapless singleton has also endured eventful dates with celebrities such as actor James Franco (along with his Japanese body pillow) and Conan O’Brien.


30 Rock,” created by Fey and inspired by her stint as head writer for “Saturday Night Live”, follows the day-to-day life of fictional NBC sketch comedy show “TGS with Tracy Jordan,” and also stars Alec Baldwin, Tracy Morgan and Jane Krakowski.


(Reporting By Piya Sinha-Roy, editing by Jill Serjeant)


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Smoking in pregnancy tied to lower reading scores

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NEW YORK (Reuters Health) – Babies exposed to their mother’s cigarette smoke in the womb later perform more poorly on reading comprehension tests, according to a new study.


“It’s not a little difference – it’s a big difference in accuracy and comprehension at a critical time when children are being assessed, and are getting a sense of what it means to be successful,” lead author Dr. Jeffrey Gruen of Yale University told Reuters Health.













In the study, researchers found that children born to mothers who smoked more than one pack per day struggled on tests specifically designed to measure how accurately a child reads aloud and if she understands what she read.


On average, children exposed to high levels of nicotine in utero — defined as the minimum amount in one pack of cigarettes per day — scored 21 percent lower in these areas than classmates born to non-smoking mothers. The difference remained even when researchers took other factors — such as if parents read books to their children, worked in lower-paying jobs or were married — into account.


Put another way, among students who share similar backgrounds and education, a child of a smoking mother will on average be ranked seven places lower in a class of 31 in reading accuracy and comprehension ability, said co-author Jan Frijters of Brock University in Ontario, Canada.


Previous studies have found smoking during pregnancy is linked to lower IQ scores and academic achievement, and more behavioral disorders. The authors found no reports so far that zeroed in on specific reading tasks like accuracy and comprehension in a large population.


The team, which published their results in The Journal of Pediatrics, pulled data from more than 5,000 children involved in the Avon Longitudinal Study of Parents and Children (ALSPC) study that began in the early 1990s in the UK. Only data from children with IQ scores of 76 and higher were used. An IQ score of 70 and below can be the sign of a mental disability.


UK researchers collected questionnaires from mothers before and after giving birth. This helps make the self-reported data more trustworthy, explained Sam Oh of the University of California, San Francisco, who wasn’t involved with the work. If mothers knew their child’s reading scores beforehand, they might subconsciously report more or less smoking.


“To me, this study suggests that the effects attributed to in utero smoking can in fact be attributed to the intrauterine environment, and not due to environmental differences that the children grow up in,” Oh told Reuters Health by email.


Large observational studies like this one call attention to patterns, but do not prove a direct cause-effect relationship between cigarette smoking and low reading scores.


Despite public health initiatives to discourage smoking, as many as one in six pregnant American women still light up, according to national surveys by the Centers for Disease Control and Prevention and the U.S. Department of Health and Human Services.


“That is a lot of children,” Dr. Tomáš Paus of the University of Toronto told Reuters Health.


Paus added that the study tied the effects of low test scores to nicotine in cigarettes, which also produce other harmful chemicals and carbon dioxide. Either way, smoking while pregnant seems to put a baby at risk for negative health outcomes.


“We should not be happy with those rates. Smoking during pregnancy is preventable,” Paus said.


SOURCE: http://bit.ly/W7v2kM The Journal of Pediatrics, online November 5, 2012.


Parenting/Kids News Headlines – Yahoo! News



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Blast rocks Gulf oil rig, two missing

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Ships and helicopters are searching for two oil rig workers who disappeared when an explosion rocked a gulf oil rig off the coast of Louisiana and set it on fire, Coast Guard officials said.


Eleven other crew members were flown to hospitals, and four of them are listed in critical condition. No one has been confirmed dead.


Earlier reports by the Coast Guard that as many as 15 people were unaccounted for were resolved as the workers were located.


Among the injured were four who were airlifted for medical treatment to the West Jefferson Medical Center, where they are in critical condition after suffering serious burns. All four are intubated and will be evacuated to Baton Rouge Burn Center when they are stabilized, according to West Jefferson spokesman Taslin Alfonzo.


Three helicopters and two rescue boats are scouring the water looking for the missing crew members, according to Ed Cubanski, chief of the U.S. Coast Guard response.


The Coast Guard said that a Black Elk Energy Co. oil and natural gas platform caught fire after workers using a torch cut a line that had 28 gallons of oil in it, causing an explosion.


Black Elk's CEO, John Hoffman, said that the wrong tool was used in cutting the line. Contract workers should have used a saw instead of a torch, which caught vapors and caused the blast. The workers were employees of Grand Isle Shipyard, not Black Elk, he said. All of the individuals were men.


The rig was offline for maintenance and was scheduled to go back online for production later this month.


There were 22 people on board at the time of the explosion, according to the Coast Guard.


An oil sheen a half mile long and 200 yards wide has spread over the water surrounding the platform, which sits in 56 feet of water. The platform was shut down for the work at the time of the accident, Cubanski said.


The platform was located about 20 nautical miles southeast of Grand Isle, La., when the explosion happened, Vega said.


The explosion and fire comes the day after BP agreed to a $4 billion settlement for the 2010 Deepwater Horizon explosion in the gulf, triggering the worst offshore oil spill in the country's history.


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France urges Mali to step up talks with rebels

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PARIS (AP) — France‘s president called Thursday for stepped-up talks between Mali’s government and any leaders from its breakaway north “who reject terrorism,” even as African nations geared up for a possible military operation against Islamic extremists there.


President Francois Hollande‘s comments suggested a growing openness to dialogue with the extremists, but he remained committed to supporting the military planning effort.













Northern Mali fell to Islamic extremists in April, after coup leaders toppled the government in Bamako, Mali‘s capital. Fearing that northern Mali could become the latest hotbed of terrorism, France has been a driving force in international efforts to bolster Mali’s army to drive the Islamists from power.


Hollande spoke with interim Mali President Dioncounda Traore by phone on Thursday, partly to detail European efforts to help strengthen Mali’s army.


In recent days, representatives from the most moderate of three al-Qaida-linked groups that control northern Mali have been meeting with Burkina Faso‘s president, appointed as a mediator.


“France reiterates its wish that political dialogue will intensify between Malian authorities and representatives of northern populations who reject terrorism,” Hollande’s office said in a statement. “The acceleration of this dialogue must accompany the progress in African military-planning efforts.”


Earlier this week, the African Union approved a plan that calls for 3,300 African troops to be deployed in order to win back Mali’s north. European countries including France and Germany have expressed a willingness to provide military trainers and logistics support, but have stopped short of committing combat troops.


France, like many European countries, fears that the arid, northern Sahel region of Mali could become a breeding ground for terrorism, where al-Qaida and its allies could plot hostage-takings and attacks in Europe or beyond.


France has millions of people whose families hail from former French colonies in north and west Africa. Authorities have long been concerned that French-born militants could travel abroad for terrorism training and return home later to possibly carry out attacks.


French authorities are already investigating two French citizens who were arrested in Mali and neighboring Niger and are suspected of seeking to join up with the al-Qaida-linked extremists, a judicial official told The Associated Press.


Ibrahim Ouattara, a 24-year-old native of the northern Paris suburb of Aubervilliers who has dual French and Malian nationality, was arrested inside Mali this month and remains in custody there, the official said.


Separately, a 27-year-old Frenchman was arrested in August in Niger and has since been handed over to authorities in France, the official said, speaking on condition of anonymity because she was not authorized to discuss terrorism cases publicly.


Europe News Headlines – Yahoo! News



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Stars honor Veloso as Latin Grammys person of year

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LAS VEGAS (AP) — Juanes, Juan Luis Guerra, Nelly Furtado and Natalie Cole are among the artists who celebrated Brazilian musician Caetano Veloso at a ceremony honoring him as the Latin Recording Academy‘s Person of the Year.


Veloso’s influence as a composer and activist also was the subject of a video featuring Sting and Spanish filmmaker Pedro Almodovar that was shown at the tribute Wednesday at the MGM Garden Arena in Las Vegas.













Veloso said in the video that he never decided to become a musician, but fate and the circumstances of life in Brazil moved him in that direction.


Considered among the most influential Brazilian artists of modern times, the 70-year-old entertainer has recorded more than 40 albums, and won eight Latin Grammys and two Grammy Awards. With his eponymous 1968 album, Veloso launched a new style of music, tropicalia, that saw his Brazilian musical roots mixed with other contemporary styles, including blues, psychedelic rock and the sounds of the Beatles.


The movement comprised a new generation of artists, including Gilberto Gil, Gal Costa and Maria Bethania, who openly expressed political opinion in their music.


In accepting the honor, Veloso said, “It’s too much.”


The Latin Grammy Awards are scheduled to be presented Thursday at the Mandalay Bay Events Center in Las Vegas. The show will be broadcast live on Univision.


___


Online:


www.latingrammy.com


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GOP-led states start warming up to health care law

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WASHINGTON (AP) — From the South to the heartland, cracks are appearing in the once-solid wall of Republican resistance to President Barack Obama‘s health care law.


Ahead of a federal deadline Friday for states to declare their intentions, Associated Press reporters interviewed governors and state officials around the country, finding surprising openness to the changes in some cases. Opposition persists in others, and there is a widespread, urgent desire for answers on key unresolved details.













The law that Republicans have derided as “Obamacare” was devised in Washington, but it’s in the states that Americans will find out if it works, delivering promised coverage to more than 30 million uninsured people.


States have a major role to play in two of the overhaul’s main components: new online insurance markets for individuals and small businesses to shop for subsidized private coverage, and an expanded Medicaid program for low-income people.


Friday is the day states must declare if they’ll build the new insurance markets, called exchanges, or let Washington do it for them. States can also opt for a partnership with the feds to run their exchanges, and they have until February to decide on that option.


Some glimpses of grudging acceptance across a shifting scene:


— One of the most visible opponents of Obama’s overhaul, Florida Republican Gov. Rick Scott, now says “if I can get to ‘yes,’ I want to get to ‘yes.’”


Florida was a leader in the failed effort to overturn the law in the Supreme Court, and a group formed by Scott ran TV ads opposing it before it passed Congress. But the governor told the AP this week he wants to negotiate with the federal government to try to help the nearly 4 million uninsured people in his state.


— In Iowa, GOP Gov. Terry Branstad says he is postponing a decision because Washington has not provided enough information about key details. But his spokesman, Tim Albrecht, said Iowa is exploring a partnership exchange that could include several states. Albrecht said they’re confident they can get to a state option if needed.


Ohio, like Florida and Iowa a state Obama carried in the election, is leaning toward a partnership with the federal government despite GOP officials’ continued misgivings about the law.


— In Mississippi, Republican insurance commissioner Mike Chaney formally notified Washington on Wednesday that his agency will proceed with a state-run exchange, disappointing GOP Gov. Phil Bryant, who remains staunchly opposed to Obama’s law.


Chaney, too, says he wishes the law could be repealed, but he worries that “if you default to the federal government, you forever give the keys to the state’s health insurance market to the federal government.”


As for trying to fight the feds, Chaney observed: “We tried that 150 years ago in the South, and it doesn’t work.”


— In New Mexico, the administration of Republican Gov. Susana Martinez had been quietly working to put the law into place as the political storm swirled. With a fifth of its population uninsured, the state is planning to run its own exchange.


“The party is over. The opposition is over,” New Mexico Human Services Secretary Sidonie Squier told the AP. “Whatever states didn’t think they were going to do it, I think they’re going to have to do it whether they like it or not. It’s a done deal now.”


Policy experts in Washington are noticing the shift.


“I think it’s a very practical decision for states now,” said Alan Weil, executive director of the nonpartisan National Academy for State Health Policy. “We are going to have a significant number of states running their own exchanges, a significant number where the federal government is running the exchange, and a significant number of partnerships. The bottom line is we are going to have to figure out how to make all three models work.”


Although the public remains divided about the health care law, the idea of states running the new insurance markets is popular, especially with Republicans and political independents. A recent AP poll found that 63 percent of Americans would prefer states to run the exchanges, with 32 percent favoring federal control.


The breakdown among Republicans was 81-17 in favor of state control, while independents lined up 65-28 for states taking the lead. Democrats were almost evenly divided, with a slim majority favoring state control.


There are several potential benefits to a state operating its own exchange, experts say.


The biggest advantage may be that states would be more closely involved in coordinating between the exchanges and Medicaid programs. Because many people are going to be going back and forth between Medicaid and private coverage in the exchanges, states would probably be better served by a hands-on role.


States can also decide whether to allow open access to all insurers, or work only with a panel of pre-screened companies that meet certain requirements.


Also, the exchanges will offer coverage to people buying in the individual and small business markets, areas that states have traditionally regulated. Without a state-run exchange, states could be dealing their own regulators out of the equation, as Mississippi’s insurance commissioner Chaney noted.


When the legislation was being considered in Congress, Democrats in the House wanted to have a national exchange administered by the federal government. But they lost the argument with their centrist Democratic counterparts in the Senate, who wanted state exchanges in order to preserve a state role.


Despite signs of movement toward going along with implementation of the overhaul, some major Republican-led states are holding fast. In Texas, the election results did not change any of the opposition to expanding Medicaid or to setting up insurance exchanges. The same holds for Louisiana, South Carolina, Missouri, Kansas and others.


“Adding more people to an already sinking ship with money that is either being borrowed from China or coming out of taxpayers’ pockets is bad policy and bad for Texans,” said Catherine Frazier, spokeswoman for Gov. Rick Perry. Twenty-seven percent of that state’s residents are uninsured, the largest percentage for any state.


Many Republican state officials complain that the Obama administration simply hasn’t given them enough information. Indeed, several major regulations affecting the exchanges have yet to be released. But that doesn’t seem to have stopped states that made an early decision to proceed.


Virginia, a Republican-led state that voted for Obama on Nov. 6 and also elected a Democratic U.S. senator, is among those defaulting to Washington. But a spokesman for Gov. Bob McDonnell said things may change.


“This is not a final decision,” said Jeff Caldwell. “The fact is, states still need far more information before any final decisions can be made on behalf of Virginia’s taxpayers.” The final call, he added, belongs to the state Legislature.


___


Associated Press writers Gary Fineout and Kelli Kennedy in Florida, Grant Schulte in Nebraska, Ann Sanner in Ohio, Jeff Amy and Emily Wagster Pettus in Mississippi, Barry Massey in New Mexico and Chris Tomlinson in Texas contributed to this report.


Health News Headlines – Yahoo! News



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A father's anguish in Gaza

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Jihad Misharawi carries his son’s body at a Gaza hospital. (AP)


Jihad Misharawi, a BBC Arabic correspondent who lives in Gaza, tragically became part of the story he's been covering on Wednesday, when an Israeli airstrike killed his 11-month-old son.


A chilling photo showing Misharawi carrying his son's body through al-Shifa hospital in Gaza City was published by the Associated Press and printed on the front page of Thursday's Washington Post.


According to Paul Danahar, the BBC's Middle East bureau chief, Misharawi's sister-in-law was also killed in the the airstrike that hit his home in Gaza. Misharawi's brother was also seriously wounded, Danahar said.


"This is a particularly difficult moment for the whole bureau in Gaza," BBC World editor Jon Williams wrote in a memo to colleagues. "We're fortunate to have such a committed and courageous team there. It's a sobering reminder of the challenges facing many of our colleagues."


At least 10 Palestinians, including Hamas military chief Ahmed al-Jabari, were killed during the Israeli airstrikes on Wednesday, Palestinians officials said.


Israel launched the operation targeting militants in response to successive days of rocket fire coming out of Gaza. Hamas, meanwhile, warned Jabari's assassination "had opened the gates of hell."


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Egypt recalls envoy to Israel after Gaza strike

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CAIRO (AP) — Egypt has recalled its ambassador to Israel after an Israeli airstrike killed the military commander of Gaza‘s ruling Hamas.


In a statement read on state TV late Wednesday, spokesman Yasser Ali said that President Mohammed Morsi recalled the ambassador and asked the Arab League‘s Secretary General to convene an emergency ministerial meeting in the wake of the Gaza violence.













Morsi also called for an immediate cease fire between Israel and Hamas, an offshoot of Morsi’s Muslim Brotherhood. Israel says it struck in response to rocket attacks from Gaza.


Hours earlier, Morsi’s Muslim Brotherhood group denounced the Israeli airstrike as a “crime that requires a quick Arab and international response to stem these massacres.”


Relations between Israel and Egypt have deteriorated since longtime President Hosni Mubarak was ousted last year.


Middle East News Headlines – Yahoo! News



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Facebook jumps on biggest lock-up expiration day

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NEW YORK (AP) — Facebook‘s stock is up more than 7 percent despite expectations that it would fall because more than 850 million additional shares in the company are being freed up for sale.


Shares of Facebook Inc. are up $ 1.48, or 7.5 percent, at $ 21.34. Facebook went public in May at $ 38 in a much-hyped initial public offering of stock that turned out to be a letdown for investors. Its stock price hasn’t hit $ 38 since.













Wednesday marked the expiration of Facebook’s biggest lock-up period, which is a time following an IPO that prevents insiders from selling stock. In all, 773 million shares became eligible for sale, along with 31 million restricted stock units. And about 48 million shares held by former Facebook employees also became eligible for sale, bringing the total to 852 million. These shares would be on top of what’s already been available for trading, increasing the supply and potentially lowering the overall price.


Lock-ups are common after initial public stock offerings and are designed to prevent a stock from experiencing the kind of volatility that might occur if too many shareholders decide to sell all at once.


The previous lock-up expired on Oct. 29, when U.S. stock markets were closed because of Superstorm Sandy. Facebook’s stock fell nearly 4 percent two days later, when the stock market reopened.


Cantor Fitzgerald analyst Youssef Squali believes a potential increase in the capital gains tax on Jan. 1, when Bush-era tax cuts would expire unless Congress acts, could pressure Facebook’s stock. That said, he called the Menlo Park, Calif.-based social media company a “long-term winner.”


Facebook’s stock saw its biggest one-day gain on Oct. 24, the day after the company reported stronger-than-expected third-quarter results and detailed for the first time how much money it made from mobile ads. The stock, which added 19 percent that day, closed at $ 23.23. Even with Wednesday’s gain, it is still 8 percent below that price.


Social Media News Headlines – Yahoo! News



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Clapton platinum watch nets $3.6 million at auction

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GENEVA (Reuters) – An Asian collector bought a platinum chronograph Patek Philippe wristwatch owned by British rock guitarist Eric Clapton for 3.44 million Swiss francs ($ 3.63 million) at auction on Monday, Christie’s said.


The “ultra-rare” reference 2499/100 by the Swiss luxury watchmaker, one of only two cased in platinum, was acquired by Clapton some 10 years ago, it said.













It fetched a combined hammer price and commission that was in line with Christie’s pre-sale estimate of 2.5-4.0 million francs while also setting a world record price for this reference at auction, it said in a statement on its semi-annual Geneva sale.


“The Eric Clapton watch was bought by an Asian private collector,” Christie’s spokesman Cristiano de Lorenzo told Reuters, adding that the buyer had been in the room.


But the top lot at the seven-hour sale was another platinum chronograph Patek Philippe, reference 2458, made in 1952 for legendary American collector J.B. Champion. It fetched nearly 3.78 million Swiss francs and set a world record for a watch without complications, or features beyond the display of hours, minutes and seconds, it said.


Precious Time, an investment watch fund launched by Luxembourg-based Elite Advisers, was the buyer, Christie’s said in a statement.


In all, 96 percent of the 315 lots on offer found new owners, netting 27.04 million Swiss francs ($ 28.52 million), the auction house owned by French billionaire Francois Pinault said.


Clapton’s Patek Philippe, made in the Swiss city in 1987, has a perpetual calendar with moon phases, as well as windows for day and month and dials for seconds and minutes.


Most experts would rank it among the world’s 10 most significant wristwatches that stand out for historical importance, mechanical complexity, beauty, original condition, rarity and superior provenance, Aurel Bacs, international head of Christie’s watch department, said before conducting the sale.


Clapton, the former Cream musician, last year sold more than 70 of his guitars at a charity auction in New York, raising $ 2.15 million for the Crossroads Centre drug and alcohol rehabilitation centre that he founded in Antigua.


Last month in London he sold an abstract painting by German artist Gerhard Richter at rival Sotheby’s for $ 34.2 million, setting a new record for the price paid at auction for the work of a living artist.


Antiquorum’s sale of modern and vintage timepieces, held in Geneva on Sunday evening, netted 8.63 million Swiss francs ($ 9.10 million) for 485 lots sold out of 613 on offer, it said in a statement issued on Monday,


The top lot was a Rolex Single Red Prototype, known as the Sea Dweller Submariner, one of only six produced in 1967 for use by divers. It sold for 490,900 Swiss francs — four time its pre-sale estimate – in its first appearance at auction.


“It is the highest price ever paid for a Rolex sport watch and for a Sea Dweller,” Antiquorum said.


($ 1 = 0.9482 Swiss francs)


(Reporting by Stephanie Nebehay; editing by Patricia Reaney)


Music News Headlines – Yahoo! News



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EU approves Bristol-Astra diabetes drug after U.S. rejection

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(Reuters) – European regulators have approved the first in a new class of diabetes medicines that work independently of insulin to control blood sugar, the drug’s developers Bristol-Myers Squibb Co and AstraZeneca Plc said on Wednesday.


The approval of Forxiga by the European Commission stands in stark contrast to the rejection of the drug in January by U.S. regulators, who cited concerns about the risk of cancer and liver injury and asked for more clinical data on the once-daily tablets.













The European Medicines Agency in April said it was satisfied those issues had been addressed in the drug’s product label and via a risk management plan for the medicine. But many industry analysts believe the drug’s dim prospects in the larger U.S. market will sharply curtail its potential sales.


The European Commission on Wednesday approved Forxiga, which works by blocking a protein called SGLT2, or sodium-glucose cotransporter 2. It is meant to be used in combination with other treatments for type 2 diabetes, including insulin, or as a standalone treatment for patients who cannot tolerate the widely used oral treatment metformin.


Bristol-Myers and AstraZeneca said Forxiga in clinical trials was associated with a low risk of hypoglycemia, a side effect of many diabetes drugs in which blood sugar drops to levels that cause fainting and other dangerous complications.


Use of the drug in clinical trials was also associated with weight loss and declines in systolic blood pressure.


Johnson & Johnson is awaiting approval of its own SGLT2 inhibitor, canagliflozin. Like Forxiga, it blocks reabsorption of glucose by the kidney and increases glucose excretion in the urine to lower blood sugar, and is also associated with drops in body weight and blood pressure.


Shares of Bristol-Myers slipped 0.8 percent to $ 31.60, while AstraZeneca fell 0.6 percent, both on the New York Stock Exchange, amid similar declines for the broad stock market.


(Reporting By Ransdell Pierson; Editing by Tim Dobbyn)


Diseases/Conditions News Headlines – Yahoo! News



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Obama warns GOP to lay off Rice attacks

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President Barack Obama speaks at his first news conference since his reelection. (Kevin Lamarque/Reuters)President Barack Obama bluntly told John McCain and other Republicans to lay off their attacks against U.N. Ambassador Susan Rice over the Benghazi assault, telling lawmakers that if they go after her "then you have a problem with me." And Obama, speaking at his first post-election press conference, vowed that Republican opposition would not dissuade him from nominating Rice to replace departing Secretary of State Hillary Clinton.


"I don't think there's any debate in this country that when you have four Americans killed that's a problem," he told reporters in the East Room of the White House. "And we've go to get to the bottom of it, and there needs to be accountability, we've got to bring those who carried it out to justice --they won't get any debate from me on that."


"But when they go after the U.N. ambassador, apparently because they think she's an easy target, then they've got a problem with me," he warned.


McCain, Senator Lindsey Graham of South Carolina, and some other Republicans have signaled they will oppose Rice's confirmation if Obama nominates her. Their numbers thus far seem far short of the 40 needed to block it, and some Republican senators have signaled that she should get a fair hearing.


"Let me say specifically about Susan Rice: She has done exemplary work. She has represented the United States and our interests in the United Nations with skill, and professionalism, and toughness, and grace," Obama said.


"And should I choose, if I think that she would be the best person to serve America in the capacity of the State Department, then I will nominate her," he vowed. "That's not a determination that I've made yet."


Rice and Democratic Senator John Kerry, who chairs the Senate Foreign Relations Committee, are seen as the front-runners in the race to succeed Clinton.


Conservatives have assailed Rice, who is close to Obama, ever since she made the rounds of the Sunday morning talk shows and said that American intelligence believed that the attack on the American compound in Benghazi, which claimed the lives of U.S. Ambassador Chris Stevens and three other Americans, grew out of demonstrations against an Internet video that ridicules Islam.


"As that unfolded, it seems to have been hijacked, let us say, by some individual clusters of extremists who came with heavier weapons, weapons that, as you know, in the wake of the revolution in Libya are quite common and accessible. And it then evolved from there," she told ABC.


White House aides have said that Rice was speaking based on the best available intelligence at the time.


"She made an appearance at the request of the White House in which she gave her best understanding of the intelligence provided to her," Obama said Wednesday. "If Senator McCain and Senator Graham want to go after somebody, they should go after me."


"But for them to go after the U.N. ambassador, who had nothing to do with Benghazi, and was simply making a presentation based on intelligence that she had received, and to besmirch her reputation is outrageous," he said.


"We're after an election now," he scolded. "I think it is important for us to find out exactly what happened in Benghazi, and I'm happy to cooperate in any ways that Congress wants. We have provided every bit of information that we have and we will continue to provide information and we've got a full-blown investigation. And all that information will be disgorged to Congress."


McCain and Graham hit back quickly.


"I have always said that the buck stops with the President of the United States," the Arizona senator said in a written statement. McCain accused Obama of "contradictory statements" about the attack, labeling it an "act of terror" the day after it happened then resisting the use of the word "terrorism" for roughly a week afterwards.


"We owe the American people and the families of the murdered Americans a full and complete explanation, which for two months the President has failed to deliver," said McCain, who has called for Congress to create a "select committee" to investigate.


"Mr. President, don't think for one minute I don't hold you ultimately responsible for Benghazi.  I think you failed as commander in chief before, during and after the attack," Graham said in a statement released by his office.


"We owe it to the American people and the victims of this attack to have full, fair hearings and accountability be assigned where appropriate. Given what I know now, I have no intention of promoting anyone who is up to their eyeballs in the Benghazi debacle," Graham said.


Obama opened what was his first press conference in months with a vow to work with both parties in Congress to tackle the so-called fiscal cliff and revive the economy. He also said he had "no evidence" that the scandal that led David Petraeus to resign in disgrace from his job as CIA director had led to breaches in classified national security material.


"Right now our economy is still recovering from a very deep and damaging crisis, so our top priority has to be jobs and growth," Obama said in opening remarks in the East Room of the White House.


"Both parties can work together" to address the fiscal challenges "in a balanced and responsible way," he said, before pushing Republicans to sign on to his call for raising taxes on the richest Americans.


Asked whether the scandal the drove Petraeus from office had led to national security breaches, Obama replied: "I have no evidence at this point, from what I've seen, that classified information was disclosed that in any way would have had a negative impact on our national security." And the president praised the retired general, saying "we are safer because of the work Dave Petraeus has done."


Asked for his appraisal of the FBI's work in bringing to light the marital infidelity that Petraeus cited in his resignation message, and why he and the American public learned of the probe only earlier this month, Obama said "I am withholding judgment" on that process but expressed "a lot of confidence generally in the FBI."


Turning to his tax battle with Republicans, Obama stuck by his vow to oppose any legislation that extends the Bush-era tax cuts for the wealthiest 2 percent of Americans. The president, asked why he had agreed to extend them in the 2010 lame duck session of Congress, said that "was a one-time proposition" and that "we cannot afford" to do so again.


Obama said he would be willing to look at raising tax revenues by closing loopholes. But he warned that doing so would probably not outweigh an estimated trillion dollars lost by extending tax cuts on income above $250,000. "The math tends not to work," he said.


"I just want to emphasize: I am open to new ideas," Obama underlined. "If the Republican counterparts or some Democrats have a great idea for us to raise revenue, maintain progressivity, make sure the middle class isn't getting hit, reduces our deficit, encourages growth, I'm not going to just slam the door in their face. I want to hear ideas from everybody."


And he reiterated that he does not want just a stopgap agreement with Congress.


"I want a big deal, I want a comprehensive deal," he said. "Fair-minded people can come to an agreement."


Obama, who won the Latino vote by a lopsided margin, also vowed to pursue comprehensive immigration reform in his second term. He said it should include border enforcement, penalties for companies that knowingly hire undocumented workers, while providing "a pathway for legal status" for those who pay their taxes and learn English. He also said it should lock in his presidential determination that undocumented immigrants brought here as children should not be deported but have a potential path to citizenship.


"We need to seize the moment," he said, predicting that "we will have a bill introduced and we begin the process in Congress very soon after my inauguration."


Obama addressed a handful of other issues:


- On the standoff over Iran's suspect nuclear program


Obama pledged to "try to make a push in the coming months to see if we can open up a dialogue between Iran and not just us but the international community, to see if we can get this thing resolved." "I can't promise that Iran will walk through the door that they need to walk though, but that would be very much the preferable option" to military action, he said.


- On the possibility of working with Republican rival Mitt Romney


Obama said that "we haven't scheduled something yet." "I think everybody needs to catch their breath. I'm sure that Governor Romney is spending some time with his family. And my hope is, before the end of the year, though, that we have a chance to sit down and talk," the president said.


- On whether he has a mandate


"I don't presume that because I won an election, that everybody suddenly agrees with me on any — everything. I'm more than familiar with all the literature about presidential overreach in second terms," Obama said. "We are very cautious about that."


"On the other hand, I didn't get re-elected just to bask in re- election. I got elected to do work on behalf of American families and small businesses all across the country who are still recovering from a really bad recession but are hopeful about the future. And I am, too."


- On climate change


Obama said he would embark "over the next several weeks, next several months" in a "wide-ranging discussion" with scientists, engineers, elected officials and others about "short-term" steps in reducing carbon emissions blamed for fueling global warming. But he seemed pessimistic about any broad response.


"I don't know what either Democrats or Republicans are prepared to do," he said. "There's no doubt that for us to take on climate change in a serious way would involve making some tough political choices."


"And you know, understandably, I think the American people right now have been so focused and will continue to be focused on our economy and jobs and growth that, you know, if the message is somehow we're going to ignore jobs and growth simply to address climate change, I don't think anybody's going to go for that. I won't go for that."


- On relations with the media. Bloomberg reporter Hans Nichols shouted out a question about taxes after Obama had indicated that he had already taken his final query.


"That was a great question, but it would be a horrible precedent for me to answer your question just because you yelled it out," he said. "So thank you very much, guys."


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General investigated for emails to Petraeus friend

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PERTH, Australia (AP) — In a new twist to the Gen. David Petraeus sex scandal, the Pentagon said Tuesday that the top American commander in Afghanistan, Gen. John Allen, is under investigation for alleged “inappropriate communications” with a woman who is said to have received threatening emails from Paula Broadwell, the woman with whom Petraeus had an extramarital affair.


Defense Secretary Leon Panetta said in a written statement issued to reporters aboard his aircraft, en route from Honolulu to Perth, Australia, that the FBI referred the matter to the Pentagon on Sunday.













Panetta said that he ordered a Pentagon investigation of Allen on Monday.


A senior defense official traveling with Panetta said Allen’s communications were with Jill Kelley, who has been described as an unpaid social liaison at MacDill Air Force Base, Fla., which is headquarters to the U.S. Central Command. She is not a U.S. government employee.


Kelley is said to have received threatening emails from Broadwell, who is Petraeus’ biographer and who had an extramarital affair with Petraeus that reportedly began after he became CIA director in September 2011.


Petraeus resigned as CIA director on Friday.


Allen, a four-star Marine general, succeeded Petraeus as the top American commander in Afghanistan in July 2011.


The senior official, who discussed the matter only on condition of anonymity because it is under investigation, said Panetta believed it was prudent to launch a Pentagon investigation, although the official would not explain the nature of Allen’s problematic communications.


The official said 20,000 to 30,000 pages of emails and other documents from Allen’s communications with Kelley between 2010 and 2012 are under review. He would not say whether they involved sexual matters or whether they are thought to include unauthorized disclosures of classified information. He said he did not know whether Petraeus is mentioned in the emails.


“Gen. Allen disputes that he has engaged in any wrongdoing in this matter,” the official said. He said Allen currently is in Washington.


Panetta said that while the matter is being investigated by the Defense Department Inspector General, Allen will remain in his post as commander of the International Security Assistance Force, based in Kabul. He praised Allen as having been instrumental in making progress in the war.


The FBI’s decision to refer the Allen matter to the Pentagon rather than keep it itself, combined with Panetta’s decision to allow Allen to continue as Afghanistan commander without a suspension, suggested strongly that officials viewed whatever happened as a possible infraction of military rules rather than a violation of federal criminal law.


Allen was Deputy Commander of Central Command, based in Tampa, prior to taking over in Afghanistan. He also is a veteran of the Iraq war.


In the meantime, Panetta said, Allen’s nomination to be the next commander of U.S. European Command and the commander of NATO forces in Europe has been put on hold “until the relevant facts are determined.” He had been expected to take that new post in early 2013, if confirmed by the Senate, as had been widely expected.


Panetta said President Barack Obama was consulted and agreed that Allen’s nomination should be put on hold. Allen was to testify at his confirmation hearing before the Senate Armed Services Committee on Thursday. Panetta said he asked committee leaders to delay that hearing.


NATO officials had no comment about the delay in Allen’s appointment.


“We have seen Secretary Panetta‘s statement,” NATO spokeswoman Carmen Romero said in Brussels. “It is a U.S. investigation.”


Panetta also said he wants the Senate Armed Services Committee to act promptly on Obama’s nomination of Gen. Joseph Dunford to succeed Allen as commander in Afghanistan. That nomination was made several weeks ago. Dunford’s hearing is also scheduled for Thursday.


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Associated Press writer Slobodan Lekic in Kabul, Afghanistan, contributed to this report.


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Verizon and HTC’s latest twist: The $199 Droid DNA

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Verizon and HTC unveiled a new device that the two hope will appeal to customers during the holiday season, while helping to reverse HTC’s floundering fortunes.


The phone, the Droid DNA, sports a 5-inch screen, putting it more in the “phablet” category with Samsung‘s Galaxy Note. It runs on Android 4.1.1 Jelly Bean and includes a boatload of powerful features, including a Super LCD 3 display with 440 pixels per inch, capable of playing 1080p HD video.













HTC noted the screen rivals traditional HDTVs, while the pixel density is among the highest available on any smartphone. The iPhone 5′s Retina display, for example, is 326 pixels per inch.


The device runs on a quad-core, 1.5Ghz Snapdragon processor from Qualcomm, with 4G LTE integrated on the same piece of silicon as the application processor. Having one chip instead of two improves battery life.


The phone is also capable of wireless charging and full HD video chat. The device has an 8-megapixel rear-facing camera and a 2.1-megapixel camera in the front. HTC noted its phone features HTC ImageSense and HTC ImageChip to create faster image processing and better quality photos, as well as a quick-launch camera option.


The Droid DNA also has Beats audio and two amplifiers, one for headphone and one for speaker. And it’s equipped with near-field communications technology to share music and other content by tapping other NFC-enabled devices.


Droid DNA goes on sale on November 21 for $ 199.99 with a two-year contract. Pre-sales begin today. The phone is available exclusively through Verizon.


The hefty specs should appeal to customers looking for alternatives to the latest gadgets from Samsung and Apple during the holiday season. For HTC, it’s pretty important that they do.


The Taiwanese handset maker really needs a hit phone. Previously the darling of the smartphone world, HTC has been having a tough time lately. Samsung and Apple are dominating the industry’s profits and market share, leaving little for HTC, Motorola, Nokia, and other handset vendors. HTC also has faced litigation, though it reached a settlement with Apple a few days ago.


The company has said it plans to go bolder with its messaging to consumers and the media, relying less on joint marketing campaigns with the carriers and standing more independently to tell the HTC story. It also has said it would try to generate buzz through social media and by seeing out influential celebrities and “superfans” for endorsements. So far, it’s unclear whether such steps are paying off.


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